Loki, Thor's half-brother, is returning, and this time he is not alone. Earth is on the verge of enslavement, and only the best of the best can save humanity.

Nick Fury, the head of the international organization Sch.I. T., collects prominent advocates of justice and goodness to repel the attack. Led by Captain America, Iron Man, Thor, The Incredible Hulk, Hawkeye and Black Widow enter the war with the invader.